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Kayano Laboratory, Obihiro University of Agriculture and Veterinary Medicine
Statistics for humans' and animals' health

Research Interests: Statistics, Bioinformatics, Data Science, Multivariate Analysis, Omics, Biomarker, Alzheimer's Disease

Publications

Omics data analyses

Detecting specific patterns in gene expression (differential coexpression)

Developing statistical methods for smoothed curves (functional data analysis)

Applications in Human Medicine

Applications in Veterinary Medicine

  • Ultrashort echo time quantitative magnetic resonance imaging of the cruciate ligaments in normal beagles
    Socha D., Pownder S., Kayano M., Matthew K., Hayashi K.,
    Veterinary and Comparative Orthopaedics and Traumatology, In Press.
  • Pathogen and severity-dependent immune responses in bovine mastitis: highlight the dynamics of differential somatic cell count
    Huang C-H, Kayano M., Kusaba N.,
    Journal of Veterinary Medical Science, 86: 7-17, 2024. [doi: 10.1292/jvms.23-0261]

  • Seasonal variation and factors affecting Trypanosoma theileri infection in wild Sika deer (Ezo Sika deer Cervus nippon yesoensis) in eastern Hokkaido
    Hong Y., Suganuma K., Ohari Y., Kayano M., Nakazaki K., Fukumoto S., Kawazu S., Inoue N.,
    Animals, 13(10): 1707, 2023. [doi:10.3390/ani13101707]

  • Serological survey of Toxoplasma gondii infection in endangered Iriomote cat (Prionailurus bengalensis iriomotensis) and simulation of the effect on population dynamics
    Shirozu T., Kayano M., Hirose F., Oshiro S., Nagamine T., Endo Y., Izawa M., Xuan X., Fukumoto S.,
    European Journal of Wildlife Research, 69:70, 2023. [doi:10.1007/s10344-023-01702-1]

  • Genetic and seasonal variations of Trypanosoma theileri and the association of Trypanosoma theileri infection
    with dairy cattle productivity in Northern Japan

    Suganuma K.*, Kayano M.*, Kida K., Gröhn Y. T., Miura R., Ohari Y., Mizushima D., Inoue N.,
    Parasitology International, 86: 102476, 2022. (*: equal contribution) [doi:10.1016/j.parint.2021.102476]

  • Effect of stem positioning on biomechanical performance of a novel cementless short stem canine total hip implant
    Ash K. J., Worden N. J., Ordway N. R., Miller M. A., Mann K. A., VanDeventer G. M., Valenzano D. M., Kayano M., Tomihari M., Hayashi K.,
    Veterinary and Comparative Orthopaedics and Traumatology, 35(01): 001-009, 2022. [doi:10.1055/s-0041-1735290]

  • Risk factors for equine trypanosomosis and hematological analysis of horses in Paraguay
    Yamazaki A., Suganuma K., Kayano M., Acosta T. J., Saitoh T., Valinott M. F. R, Sanchez A. R., Inoue N.,
    Acta Tropica, 233: 106543, 2022. [doi.org/10.1016/j.actatropica.2022.106543]

  • Effect of the locational relationship between the 1st wave dominant follicle and the corpus luteum on conception
    rate after embryo transfer: data analysis of 297 embryo transfers from a commercial embryo production program

    Goto A., Hayama K., Urakawa M., Oono Y., Hazano K., Kayano M., Haneda S., Nakada K., Matsui M.,
    Journal of the Hellenic Veterinary Medical Society, 73(1): 3635-3640, 2022. [doi.org/10.12681/jhvms.25366]

  • Age-related arteriolar changes with lipid and amyloid deposits in the genital organs of dogs
    Ushio N., Chambers J. K., Watanabe K., Kayano M., Uchida K.,
    Veterinary Pathology, 58(3): 558-567, 2021. [doi:10.1177/0300985821996670]

  • Is Salmonella enterica shared between wildlife and cattle in cattle farming areas? An eleven-year retrospective study in Tokachi district, Hokkaido, Japan
    Yamaguchi E., Fujii K., Kayano M., Sakurai Y., Nakatani A., Sasaki M., Hertl J. A., Gröhn Y. T.,
    Veterinary Medicine and Science, 1–13, 2021. [doi:10.1002/vms3.685]

  • Fertility risk factors in transferring Japanese Black embryos into dairy heifers: an epidemiological study
    Goto A., Hayama K., Urakawa M., Oono Y., Hazano K., Kayano M., Haneda S., Nakada K., Gröhn Y. T., Matsui M.,
    Veterinary and Animal Science, 13: 100193, 2021. [doi:10.1016/j.vas.2021.100193]

  • Associations between plasma testosterone levels and season, nutritional status, age, and body size
    in free-ranging male Asian black bears (Ursus thibetanus) in central Honshu, Japan

    Tomiyasu J., Kayano M., Hazano K., Matsui M., Nemoto Y., Naganuma T., Koike S. and Yamazaki K.,
    General and Comparative Endocrinology, 309: 113794, 2021. [doi:10.1016/j.ygcen.2021.113794]

  • Effects of the formation and regression of accessory corpus luteum during pregnancy on plasma
    concentration of progesterone and pregnancy status in cross-bred beef heifers

    Hazano K., Miki T., Goto A., Kayano M., Haneda S., Văn D. B., Miura R., Matsui M.,
    Animal Reproduction Science, 232: 106825, 2021. [doi:10.1016/j.anireprosci.2021.106825]

  • Local sex steroid hormone milieu in the bovine oviduct ipsilateral and contralateral to preovulatory follicle or corpus luteum during the periovulatory phase
    Hazano K., Haneda S., Kayano M., Matsui M., Domestic Animal Endocrinology, 74: 106515, 2021. [doi:10.1016/j.domaniend.2020.106515]
  • Mobility of the forearm skeleton in the Asiatic black (Ursus thibetanus), brown (U. arctos) and polar (U. maritimus) bears
    Amaike H., Sasaki M., Tsuzuki N., Kayano M., Oishi M., Yamada K., Endo H., Anezaki T., Matsumoto N.,
    Nakashita R., Kuroe M., Taru H., Bando G., Iketani Y., Nakamura R., Sato N., Fukui D. and Kitamura N.,
    The Journal of Veterinary Medical Science, 83(8): 1284–1289, 2021. [doi:10.1292/jvms.21-0198]
  • Research on growth curve and suitable slaughter weight of the mangalica pig
    Takatani R., Yamane K., Kosaka K., Kayano M., Hagiya K., Mikami N., Hayashida S., Miyashita T., Koide A., Yamaguchi Y., Muranish Y.,
    Hokkaido Society of Livestock and Grassland Science, 9: 1-11, 2021. (In Japanese)

  • The relationship between Moraxella bovoculi and the severity of ocular lesions in heifers in a dairy
    farm with a high incidence of infectious bovine keratoconjunctivitis

    Chiba Y., Itoh M., Tsuchiya H., Kusumoto A., Kayano M., Takahashi E., Jpn. J. Large Anim. Clin, 12(1): 21-26, 2021. (In Japanese)
  • Epidemiological analysis of avulsion fractures in dogs
    Matos Cruz A.M., Kayano M., Tomihari M., Chou P.Y., Kim S.Y., Kapatkin A.S., Hayashi K.,
    Veterinary and Comparative Orthopaedics and Traumatology, e60-e65, 2020. [doi:10.1055/s-0040-1713123]
  • Radiographic and biomechanical assessment of three implant designs for canine cementless total hip replacement
    Worden N.J., Ash K.J., Ordway N.R., Miller M.A., Mann K.A., VanDevnter G.M., Valenzano D.M., Hart R., Kayano M., Hayashi K.,
    Veterinary and Comparative Orthopaedics and Traumatology, 2020. [doi:10.1055/s-0040-1715476]

  • Nationwide serological surveillance of non-tsetse-transmitted horse trypanosomoses in Mongolia
    Mizushima D., Amgalanbaatar T., Davaasuren B., Naransatsral S., Myagmarsuren P., Otgonsuren D., Enkhtaivan B., Davkharbayar B., Mungun-Ochir B.,
    Baatarjargal P., Nyamdolgor U., Soyolmaa G., Kayano M., Nguyen T.T., Battsetseg B., Battur B., Inoue N., Yokoyama N., Suganuma K.,
    Parasite Epidemiology and Control, 10: e00158, 2020. [doi:10.1016/j.parepi.2020.e00158]

  • Blood markers of osteoclastic differentiation in periparturient dairy cows at different parities, with and without milk fever
    Hatate K., Kawashima C., Kayano M., Hanada M., Yamagishi N.,
    Research in Veterinary Science, 131: 301-305, 2020. [doi:10.1016/j.rvsc.2020.05.009]

  • Behavioral effects of scents from male mature Rathke glands on juvenile green sea turtles (Chelonia mydas) via olfactory acuity
    Kitayama C., Yamaguchi Y., Kondo S., Ogawa R., Kawai Y., Kayano M., Tomiyasu J., Kondoh D.,
    Journal of Veterinary Medical Science, 82(9): 1312-1315, 2020. [doi: 10.1292/jvms.20-0058]

  • Effects of hCG administration on corpus luteum development and plasma sex steroid hormone concentration in beef heifers
    differ according to the locational relationships of the original corpus luteum and the first-wave dominant follicle

    Hazano K., Haneda S., Kayano M., Miura R., Matsui M., Journal of Veterinary Medical Science, 82 (8):1219-1225, 2020. [doi:/10.1292/jvms.20-0199]
  • Possible roles of the local oviductal estradiol-17 beta in luteal formation phase on the function of bovine oviductal epithelium
    Hazano K., Haneda S., Kayano M., Matsui M., Journal of Veterinary Medical Science, 81(12): 1817-1823, 2019. [doi: 10.1292/jvms.19-0411]
  • The effect of colostrum intake on osteoprotegerin and bone metabolic markers in the blood of newborn calves during the first week of life
    Hatate K., Kayano M., Kawashima C., Hanada M., Bicalho R. C. and Yamagishi N.,
    Journal of Veterinary Medical Science, 81(1): 15-21, 2019. [doi: 10.1292/jvms.18-0453]
  • Effect of fermented beverage of plant extract by-product (FPEB)for meat production and gut microbiota in barrows
    Muranishi Y., Umeda K., Saito E., Hayashida S., Nagata R., Inamori J., Hirata H., Kayano M., Okada H., Han K.,Fukushima M., Shimada K.,
    Hokkaido Society of Livestock and Grassland Science, 7:39-45, 2019. (In Japanese)
  • Associations of the first occurrence of pathogen-specific clinical mastitis with milk yield and milk composition in dairy cows
    Kayano M., Ito M., Kusaba N., Hayashiguchi O., Kida K., Tanaka Y., Kawamoto K. and Grohn Y. Journal of Dairy Research, 85(3):309-316, 2018.
  • Short Communication: Serum osteoprotegerin concentrations in periparturient dairy cows
    Hatate K., Kawashima C., Hanada M., Kayano M.and Yamagishi, N. Journal of Dairy Science, 101 (7): 6622-6626, 2018.
  • Testosterone-related and seasonal changes in sebaceous glands in the back skin of adult male brown bears (Ursus arctos)
    Tomiyasu J., Yanagawa Y., Sato Y., Nagano M., Sasaki M., Sakamoto H., Matsumoto N., Kobayashi K., Kayano M., Haneda S. and Matsui M.,
    Canadian Journal of Zoology, 96(3): 205-211, 2018.
  • Discriminant analysis for prediction and classification of tick-borne infections in some dairy cattle herds at Dakahlia Governorate, Egypt
    EI-Fadl E.A., EI-Ashker M., Suganuma K., Kayano M., Japanese Journal of Veterinary Research, 65(3): 127-133, 2017.
  • Risk factors for stillbirths and mortality during the first 24 hours of life on dairy farms in Hokkaido, Japan, 2005 to 2009
    Kayano M., Kadohira M. and Steavenson, M. A., Preventive Veterinary Medicine, 127(1):50-55, 2016.
  • Identifying alterations in metabolic profiles of dairy cows over the past two decades in Japan using principal component analysis
    Kayano M. and Kida K., Journal of Dairy Science, 98(12): 8764-8774, 2015.
  • Screening for ketosis using multiple logistic regression based on milk yield and composition
    Kayano M. and Kataoka T., The Journal of Veterinary Medical Science, 77(11): 1473-1478, 2015.
  • Experimental assessment of bone mineral density using quantitative computed tomography in Holstein dairy cows.
    Maetani, A., Itoh, M., Nishihara, K., Aoki, T., Ohtani, M. Shibano, K., Kayano M. and Yamada, K.,
    The Journal of Veterinary Medical Science, 78 (7): 1209-1211, 2016.
  • Differences in progesterone concentrations and mRNA expressions of progesterone receptors in bovine endometrial tissue
    between uterine born ipsilateral and contralateral to the corpus luteum

    Takahashi H., Haneda S., Kayano M. and Matsui M., The Journal of Veterinary Medical Science, 78 (4): 613-618, 2016.
  • Distribution of follicles in canine ovary -A simple and rapid method for counting follicles-
    Hayashi M., Hariya M., Kayano M. and Suzuki H., Cryobiology, 71: 514-517, 2015.
  • Development of the first follicular wave dominant follicle on the ovary ipsilateral to the corpus luteum
    is associated with decreased conception rate in dairy cattle

    Miura R., Haneda S., Kayano M. and Matsui M., Journal of Dairy Science, 98(1): 318-321, 2015.
  • Experimental investigation of bone mineral density in thoroughbreds using quantitative computed tomography
    Yamada, K., Sato, F., Higuchi, T., Nishihara, K., Kayano M., Sasaki, N. and Nambo, Y., The Journal of Equine Science, 26(3):81-87, 2015.
  • Relationship between the placental retention time and the reproductive performance
    at the foal heat in thoroughbred and a comparison with heavy draft

    Ishii M., Aoki T., Yamakawa K., Magata F., Gojo C., Ito K., Kayano M. and Nambo Y., Journal of Equine Science, 24(2): 25-29, 2013.

Applications in Agriculture


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[ Obihiro University of Agriculture and Veterinary Medicine | Department of Animal and Food Hygiene | Field Center of Animal Science and Agriculture ]